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Anti-FKBP1B Polyclonal Antibody

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货号 TMAB-06045

Anti-FKBP1B Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FKBP1B。Anti-FKBP1B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-FKBP1B Polyclonal Antibody

Anti-FKBP1B Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06045

Anti-FKBP1B Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FKBP1B。Anti-FKBP1B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-FKBP1B Polyclonal Antibody is a Rabbit antibody targeting FKBP1B. Anti-FKBP1B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Isoform 1 and isoform 2 are Ubiquitous with highest levels in brain and thymus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human FKBP1B
抗原种属
Human
基因名称
FKBP1B
基因ID
蛋白名称
Peptidyl-prolyl cis-trans isomerase FKBP1B
Uniprot ID
功能
Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
化学信息
分子量Theoretical: 12 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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