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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PGRMC Polyclonal Antibody

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货号 TMAB-10253

Anti-PGRMC Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PGRMC。Anti-PGRMC Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PGRMC Polyclonal Antibody

Anti-PGRMC Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10253

Anti-PGRMC Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PGRMC。Anti-PGRMC Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PGRMC Polyclonal Antibody is a Rabbit antibody targeting PGRMC. Anti-PGRMC Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Microsome membrane; Single-pass membrane protein (By similarity). Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity).
组织特异性Widely expressed, with highest expression in liver and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PGRMC1 is a progesterone receptor component of 195 aa with a 26 residue N terminal hydrophobic region and no N terminal glycosylation site. It has an overall homology of 50% with PGRMC2 but their C terminal regions have a 68% homology, including a highly conserved 58 residue sequence.PGRMC1 is a heme bind proteins that is up-regulated in several cancers. In breast tumors, PGRMC1 is associated with hypoxia estrogen receptor-negative status. PGRMC1 is also shown to stimulate AKT phosphorylation and is known to stabilise the EGFR receptor tyrosine kinase.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PGRMC
抗原种属
Human
基因名称
PGRMC1
基因ID
10857
蛋白名称
Membrane-associated progesterone receptor component 1
Uniprot ID
O00264
功能
Receptor for progesterone (By similarity).
化学信息
分子量Theoretical: 21 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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