购物车
- 全部删除
您的购物车当前为空
Anti-Cadherin 16/CDH16 Antibody (4F686)
还可以产品编号 TMAY-01325
Anti-Cadherin 16/CDH16 Antibody (4F686) 是一种 Mouse 抗体，靶向 Cadherin 16/CDH16。Anti-Cadherin 16/CDH16 Antibody (4F686) 可用于 ELISA(Cap)。
Anti-Cadherin 16/CDH16 Antibody (4F686)
Anti-Cadherin 16/CDH16 Antibody (4F686)
还可以产品编号 TMAY-01325
Anti-Cadherin 16/CDH16 Antibody (4F686) 是一种 Mouse 抗体，靶向 Cadherin 16/CDH16。Anti-Cadherin 16/CDH16 Antibody (4F686) 可用于 ELISA(Cap)。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Cadherin 16/CDH16 Antibody (4F686) is a Mouse antibody targeting Cadherin 16/CDH16. Anti-Cadherin 16/CDH16 Antibody (4F686) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4F686 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KSP-Cadherin / Cadherin-16 (rh KSP-Cadherin / Cadherin-16; TMPY-01763; NP_004053.1; Met1-Ala786). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | KSP-Cadherin/Cadherin-16 is a member of the cadherin superfamily, calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. KSP-Cadherin/Cadherin-16 can be detected at later stages of tubulogenesis during human renal development and in the distal tubules of adult kidneys, no expression was found by immunohistochemistry or Western blot analysis in RCC tumour tissues and several RCC cell lines. However, despite the lack of protein expression, mRNA synthesis of KSP-Cadherin/Cadherin-16 could be detected by reverse transcriptase-polymerase chain reaction analysis in all RCC tissues and most of the RCC cell lines studied, although at a reduced level. The loss of KSP-Cadherin/Cadherin-16 protein was only observed in the malignant part of the tumour kidneys, whereas in the normal part of the affected kidneys KSP-Cadherin/Cadherin-16 expression was clearly detected. These results indicate a downregulation of Ksp-cadherin in RCC and suggest a role for this cell adhesion molecule in tumour suppression. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human KSP-Cadherin / Cadherin-16 Protein (TMPY-01763) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-Cadherin 16/CDH16 Antibody (4F686) | purchase Anti-Cadherin 16/CDH16 Antibody (4F686) | Anti-Cadherin 16/CDH16 Antibody (4F686) cost | order Anti-Cadherin 16/CDH16 Antibody (4F686)
嗨！有任何问题？点我咨询
评论内容