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Anti-BDKRB1 Polyclonal Antibody
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产品编号 TMAB-00204
Anti-BDKRB1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BDKRB1。Anti-BDKRB1 Polyclonal Antibody 可用于 WB。
Anti-BDKRB1 Polyclonal Antibody
Anti-BDKRB1 Polyclonal Antibody
还可以产品编号 TMAB-00204
Anti-BDKRB1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BDKRB1。Anti-BDKRB1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-BDKRB1 Polyclonal Antibody is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse (predicted:Rat,Rabbit) |
| 验证活性 | 1. Sample: Lane 1: Human Siha cell lysates Lane 2: Human LOVO cell lysates Lane 3: Human K562 cell lysates Lane 4: Human A549 cell lysates Lane 5: Human Hela cell lysates Primary: Anti-BDKRB1 (TMAB-00204) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 60 kDa 2. Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Human SiHa cell lysates Lane 3: Human LOVO cell lysates Lane 4: Human K562 cell lysates Lane 5: Human U251 cell lysates Primary: Anti-BDKRB1 (TMAB-00204) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 60 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Kinins are important biologically active peptides that mediate cardiovascular homeostasis, inflammation and nociception. Bradykinin, the major effector peptide of the kallikrein-kinin system, is regulated by angiotensin-converting enzyme (ACE), which degrades the peptide. Bradykinin normally exerts its effects through the activation of two seven transmembrane G-protein coupled receptors, named B1 and B2. The B2 receptor is constitutively expressed and preferentially binds full length bradykinin. Deletion of the B2 receptor leads to salt-sensitive hypertension and altered nociception in mice. The B1 receptor binds to derivatives of bradykinin and kallidin, which are produced by carboxypeptidase action to generate the products des-Arg9-bradykinin and des-Arg10-kallidin, respectively. The expression of the B1 receptor is inducible by inflammatory mediators, such as bacterial lipopolysaccharide (LPS) and cytokines. The B1 and B2 receptors represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases. |
| 免疫原 | KLH conjugated synthetic peptide: Human BDKRB1 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Macrophage / Inflamm.,Vitamins / minerals,Cancer,Vitamins / Minerals,Calcium Signaling,GPCR |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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