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顶部生物活性储存和溶解信息计算器

Anti-PPAR delta+beta Polyclonal Antibody

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产品编号 TMAB-11652

种类：Rabbit Polyclonal
应用：WB,IHC-P,IHC-Fr,IF
交叉反应：Mouse (predicted:Rat)

Anti-PPAR delta+beta Polyclonal Antibody

Anti-PPAR delta+beta Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-11652

种类：Rabbit Polyclonal
应用：WB,IHC-P,IHC-Fr,IF
交叉反应：Mouse (predicted:Rat)

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产品介绍

生物活性
产品描述
Anti-PPAR delta+beta Polyclonal Antibody is a Rabbit antibody targeting PPAR delta+beta. Anti-PPAR delta+beta Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Mouse (predicted:Rat)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Ubiquitous with maximal levels in placenta and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Heterodimer with the retinoid X receptor. Subcellular located at nuclear Tissue specificity: Heart, adrenal and intestine. Belongs to the nuclear hormone receptor family. NR1 subfamily. It Contains 1 nuclear receptor DNA-binding domain.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse PPAR delta + beta
抗原种属
Mouse
基因名称
PPARD
基因ID
19015
蛋白名称
Peroxisome proliferator-activated receptor delta
Uniprot ID
P35396
功能
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
化学信息
分子量Theoretical: 48 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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