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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-KCNK3 Polyclonal Antibody 2

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货号 TMAB-07940

Anti-KCNK3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 KCNK3。Anti-KCNK3 Polyclonal Antibody 2 可用于 WB。

Anti-KCNK3 Polyclonal Antibody 2

Anti-KCNK3 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-07940

Anti-KCNK3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 KCNK3。Anti-KCNK3 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-KCNK3 Polyclonal Antibody 2 is a Rabbit antibody targeting KCNK3. Anti-KCNK3 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein (Potential).
组织特异性Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents. KCNK9 gene has been localized to the chromosomal region 8q24. The protein is expressed at high levels mainly in the brain and at low levels in other tissues. In contrast to normal tissues, it was found that KCNK9 is amplified in some human carcinomas such as breast, lung, colon and metastatic prostate. In 10% of breast cancer patients this gene is amplified, and in 44% the protein is over expressed. Monoclonal antibodies to KNCK9 are an important tool for studying the potassium channel family of proteins in different tissues.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KCNK3
抗原种属
Human
基因名称
KCNK3
基因ID
3777
蛋白名称
Potassium channel subfamily K member 3
Uniprot ID
O14649
功能
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.
化学信息
分子量Theoretical: 43 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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