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Anti-TROP-2 Antibody-FITC (1P681)
还可以产品编号 TMAY-00816F
Anti-TROP-2 Antibody-FITC (1P681) 是一种 FITC-conjugated Rabbit 抗体，靶向 TROP-2。Anti-TROP-2 Antibody-FITC (1P681) 可用于 FCM。
Anti-TROP-2 Antibody-FITC (1P681)
Anti-TROP-2 Antibody-FITC (1P681)
还可以产品编号 TMAY-00816F
Anti-TROP-2 Antibody-FITC (1P681) 是一种 FITC-conjugated Rabbit 抗体，靶向 TROP-2。Anti-TROP-2 Antibody-FITC (1P681) 可用于 FCM。
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产品介绍
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抗原信息
| 产品描述 | Anti-TROP-2 Antibody-FITC (1P681) is a FITC-conjugated Rabbit antibody targeting TROP-2. Anti-TROP-2 Antibody-FITC (1P681) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1P681 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of anti-Human TROP2 on MCF-7 cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human TROP2 / TACSTD2 (rh TROP2 / TACSTD2; TMPY-01262; NP_002344.2; Met1-Thr274) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human TROP2 / TACSTD2 protein (TMPY-01262) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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