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SLAM/CD150 Protein, Rat, Recombinant (His)

SLAM/CD150 Protein, Rat, Recombinant (His)

产品编号 TMPY-03667
别名: signaling lymphocytic activation molecule family member 1

SLAM/CD150 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is D3ZAD7.

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SLAM/CD150 Protein, Rat, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 5日内发货
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产品目录号及名称: SLAM/CD150 Protein, Rat, Recombinant (His) (TMPY-03667)
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产品描述 SLAM/CD150 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is D3ZAD7.
种属 Rat
表达系统 HEK293 Cells
标签 C-His
蛋白编号 D3ZAD7
别名 signaling lymphocytic activation molecule family member 1
蛋白构建 The Rat SLAMF1 (D3ZAD7) (Met1-Leu242) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 17.4 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of interferon γ (IFN-γ) in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus.

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Keywords

SLAM/CD150 Protein, Rat, Recombinant (His) signaling lymphocytic activation molecule family member 1 recombinant recombinant-proteins proteins protein

 

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