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Anti-TROP-2 Antibody (6F304)

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Anti-TROP-2 Antibody (6F304)
产品编号 TMAY-03490
别名 tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1

Anti-TROP-2 Antibody (6F304) 是一种 Rabbit 抗体,靶向 TROP-2。Anti-TROP-2 Antibody (6F304) 可用于 IHC-P。

Anti-TROP-2 Antibody (6F304)
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Anti-TROP-2 Antibody (6F304)

Rating icon 还可以
Anti-TROP-2 Antibody (6F304)
产品编号 TMAY-03490 别名 tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1

Anti-TROP-2 Antibody (6F304) 是一种 Rabbit 抗体,靶向 TROP-2。Anti-TROP-2 Antibody (6F304) 可用于 IHC-P。

规格价格库存数量
20 μL
¥ 785
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-TROP-2 Antibody (6F304) is a Rabbit antibody targeting TROP-2. Anti-TROP-2 Antibody (6F304) can be used in IHC-P.
别名tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1
Ig Type
Rabbit IgG
克隆号
6F304
交叉反应
Mouse, Rat;
Not React with:Human, Rhesus/Cynomolgus
验证活性
1. Immunochemical staining of mouse TACSTD2 in mouse skin with rabbit monoclonal antibody (1:20000, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of mouse TACSTD2 in mouse kidney with rabbit monoclonal antibody (1:20000, formalin-fixed paraffin embedded sections).
应用
IHC-P
推荐剂量
IHC-P: 1:10000-1:20000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TROP-2 / TACSTD2 (rM TROP-2 / TACSTD2; TMPY-02667; Q8BGV3; Met1-Gln270).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse TROP-2 / TACSTD2 protein (TMPY-02667)
抗原种属
Mouse
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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