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Transferrin Receptor/TFRC Protein, Human, Recombinant (C-hFc)
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货号 TMPK-00376
别名 TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 101.8 kDa and the accession number is P02786-1.
其他形式的 “Transferrin Receptor/TFRC Protein, Human, Recombinant (C-hFc)”:
Transferrin Receptor/TFRC Protein, Human, Recombinant (C-hFc)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPK-00376 别名 TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 101.8 kDa and the accession number is P02786-1.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 268 | 6-8日内发货 | |
| 10 μg | ¥ 419 | 6-8日内发货 | |
| 20 μg | ¥ 678 | 5日内发货 | |
| 50 μg | ¥ 1,320 | 5日内发货 | |
| 100 μg | ¥ 2,210 | 5日内发货 | |
| 200 μg | ¥ 3,930 | 5日内发货 | |
| 500 μg | ¥ 8,900 | 5日内发货 |
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| 产品描述 | The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 101.8 kDa and the accession number is P02786-1. |
| 生物活性 | 1. Immobilized Human Transferrin R, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-Transferrin R Antibody, hFc Tag with the EC50 of 26.5ng/ml determined by ELISA (QC Test).
2. Human Transferrin R, hFc Tag captured on CM5 Chip via Anti-Fc Antibody can bind Human Transferrin, His Tag with an affinity constant of 0.1μM as determined in SPR assay. |
| 研究背景 | The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-hFc |
| 蛋白编号 | P02786-1 |
| 蛋白构建 | Cys89-Phe760 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71 |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 101.8 kDa (predicted). Due to glycosylation, the protein migrates to 105-115 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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