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Anti-Claudin6 Antibody (6A290)
还可以产品编号 TMAY-02829
Anti-Claudin6 Antibody (6A290) 是一种 Mouse 抗体，靶向 Claudin6。Anti-Claudin6 Antibody (6A290) 可用于 WB。
Anti-Claudin6 Antibody (6A290)
Anti-Claudin6 Antibody (6A290)
还可以产品编号 TMAY-02829
Anti-Claudin6 Antibody (6A290) 是一种 Mouse 抗体，靶向 Claudin6。Anti-Claudin6 Antibody (6A290) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 6A290 |
| 交叉反应 | Human |
| 验证活性 | Anti-Claudin-6 mouse monoclonal antibody at 1:1000 dilution. -Lane A: Recombinant Human Claudin-6 Protein, VLP 500ng -Lane B: Virus-Like Particle (VLP) isotype control Protein 500ng -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with Human Claudin6 mRNA. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Claudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing. |
| 偶联 | Unconjugated |
| 免疫原 | Human Claudin6 mRNA |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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