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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NIMP/RTN4IP1 Polyclonal Antibody

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货号 TMAB-09479

Anti-NIMP/RTN4IP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NIMP/RTN4IP1。Anti-NIMP/RTN4IP1 Polyclonal Antibody 可用于 WB。

Anti-NIMP/RTN4IP1 Polyclonal Antibody

Anti-NIMP/RTN4IP1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09479

Anti-NIMP/RTN4IP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NIMP/RTN4IP1。Anti-NIMP/RTN4IP1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,975
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200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-NIMP/RTN4IP1 Polyclonal Antibody is a Rabbit antibody targeting NIMP/RTN4IP1. Anti-NIMP/RTN4IP1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion.
组织特异性Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Appears to be a potent inhibitor of regeneration following spinal cord injury.Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Nogo is expressed by oligodendrocytes but not by Schwann cells, and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo-A, -B and -C. NIMP (NOGO-interacting mitochondrial protein), also known as RTN4IP1 (Reticulon-4-interacting protein 1), is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation. NIMP is expressed in mitochondrial-rich tissue such as kidney, heart, skeletal muscle and specific regions within the nervous system. Through interaction with Nogo, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth. There are three isoforms of NIMP that are produced as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NIMP/RTN4IP1
抗原种属
Human
基因名称
RTN4IP1
基因ID
84816
蛋白名称
Reticulon-4-interacting protein 1, mitochondrial
Uniprot ID
Q8WWV3
功能
Appears to be a potent inhibitor of regeneration following spinal cord injury.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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