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Anti-NPPB Antibody (6G519)

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产品编号 TMAH-00823
别名 γ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP

Anti-NPPB Antibody (6G519) 是一种 Mouse 抗体,靶向 NPPB。Anti-NPPB Antibody (6G519) 可用于 ELISA, IHC。

Anti-NPPB Antibody (6G519)

Anti-NPPB Antibody (6G519)

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产品编号 TMAH-00823 别名 γ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP

Anti-NPPB Antibody (6G519) 是一种 Mouse 抗体,靶向 NPPB。Anti-NPPB Antibody (6G519) 可用于 ELISA, IHC。

规格价格库存数量
50 μg
¥ 1,315
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100 μg
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-NPPB Antibody (6G519) is a Mouse antibody targeting NPPB. Anti-NPPB Antibody (6G519) can be used in ELISA, IHC.
别名γ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP
Ig Type
IgG2b
克隆号
6G519
交叉反应
Human
验证活性
1. Immunohistochemistry of paraffin-embedded human brain using TMAH-00823 in 30μg/ml dilute concentrations.
2. Immunohistochemistry of paraffin-embedded human heart using TMAH-00823 in 30μg/ml dilute concentrations.
3. Immunohistochemistry of paraffin-embedded human brain using TMAH-00823 in 30μg/ml dilute concentrations.
4. Immunohistochemistry of paraffin-embedded human heart using TMAH-00823 in 30μg/ml dilute concentrations.
应用
ELISA, IHC
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位[NT-proBNP]: Secreted.; [proBNP(3-108)]: Secreted.; [Brain natriuretic peptide 32]: Secreted.; [BNP(3-32)]: Secreted.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
纯度>95%
研究背景Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3. May affect cardio-renal homeostasis. Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32. May have a role in cardio-renal homeostasis. Able to promote the production of cGMP.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human NPPB Protein
抗原种属
Human
基因ID
4879
Uniprot ID
研究领域
Signal Transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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