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Anti-NPPB Antibody (6G519) 是一种 Mouse 抗体,靶向 NPPB。Anti-NPPB Antibody (6G519) 可用于 ELISA, IHC。
Anti-NPPB Antibody (6G519) 是一种 Mouse 抗体,靶向 NPPB。Anti-NPPB Antibody (6G519) 可用于 ELISA, IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μg | ¥ 1,315 | 5日内发货 | |
100 μg | ¥ 2,190 | 5日内发货 |
产品描述 | Anti-NPPB Antibody (6G519) is a Mouse antibody targeting NPPB. Anti-NPPB Antibody (6G519) can be used in ELISA, IHC. |
别名 | γ-brain natriuretic peptide, NPPB, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP |
Ig Type | IgG2b |
克隆号 | 6G519 |
交叉反应 | Human |
验证活性 | 1. Immunohistochemistry of paraffin-embedded human brain using TMAH-00823 in 30μg/ml dilute concentrations. 2. Immunohistochemistry of paraffin-embedded human heart using TMAH-00823 in 30μg/ml dilute concentrations. 3. Immunohistochemistry of paraffin-embedded human brain using TMAH-00823 in 30μg/ml dilute concentrations. 4. Immunohistochemistry of paraffin-embedded human heart using TMAH-00823 in 30μg/ml dilute concentrations. |
应用 | ELISA, IHC |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
亚细胞定位 | [NT-proBNP]: Secreted.; [proBNP(3-108)]: Secreted.; [Brain natriuretic peptide 32]: Secreted.; [BNP(3-32)]: Secreted. |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Protein G purified |
性状 | Liquid |
缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
纯度 | >95% |
研究背景 | Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3. May affect cardio-renal homeostasis. Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32. May have a role in cardio-renal homeostasis. Able to promote the production of cGMP. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: Human NPPB Protein |
抗原种属 | Human |
基因ID | 4879 |
Uniprot ID | |
研究领域 | Signal Transduction |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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