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Anti-Neurotensin Receptor 2 Polyclonal Antibody

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货号 TMAB-09410

Anti-Neurotensin Receptor 2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Neurotensin Receptor 2。Anti-Neurotensin Receptor 2 Polyclonal Antibody 可用于 WB。

Anti-Neurotensin Receptor 2 Polyclonal Antibody

Anti-Neurotensin Receptor 2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09410

Anti-Neurotensin Receptor 2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Neurotensin Receptor 2。Anti-Neurotensin Receptor 2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-Neurotensin Receptor 2 Polyclonal Antibody is a Rabbit antibody targeting Neurotensin Receptor 2. Anti-Neurotensin Receptor 2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Neurotensin Receptor 2
抗原种属
Human
基因名称
NTSR2
基因ID
蛋白名称
Neurotensin receptor type 2
Uniprot ID
功能
Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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