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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MCM7 Antibody (7Z6)

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货号 TMAB-08673

Anti-MCM7 Antibody (7Z6) 是一种 Rabbit 抗体，靶向 MCM7。Anti-MCM7 Antibody (7Z6) 可用于 WB,IHC-P,IF,IHC-Fr。

Anti-MCM7 Antibody (7Z6)

Anti-MCM7 Antibody (7Z6)

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Rating icon 还可以
货号 TMAB-08673

Anti-MCM7 Antibody (7Z6) 是一种 Rabbit 抗体，靶向 MCM7。Anti-MCM7 Antibody (7Z6) 可用于 WB,IHC-P,IF,IHC-Fr。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-MCM7 Antibody (7Z6) is a Rabbit antibody targeting MCM7. Anti-MCM7 Antibody (7Z6) can be used in WB,IHC-P,IF,IHC-Fr.
Ig Type
IgG
克隆号
7Z6
反应种属
Human
应用WBIHC-PIFIHC-Fr
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IF: 1:50-200; IHC-Fr: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human MCM7
抗原种属
Human
基因名称
MCM7
基因ID
4176
蛋白名称
DNA replication licensing factor MCM7
Uniprot ID
P33993
功能
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
化学信息
分子量Theoretical: 79 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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