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C5AR1 Protein-VLP, Human, Recombinant (His)

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货号 TMPH-01022

别名 CD88, C5R1, C5AR1, C5AR, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR)

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 41.1 kDa and the accession number is P21730.

C5AR1 Protein-VLP, Human, Recombinant (His)
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C5AR1 Protein-VLP, Human, Recombinant (His)

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货号 TMPH-01022 别名 CD88, C5R1, C5AR1, C5AR, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR)

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 41.1 kDa and the accession number is P21730.

规格价格库存数量
5 μg
¥ 1,730
20日内发货
10 μg
¥ 2,920
20日内发货
20 μg
¥ 4,930
20日内发货
50 μg
¥ 7,930
20日内发货
100 μg
¥ 11,800
20日内发货
200 μg
¥ 19,900
20日内发货
500 μg
¥ 39,800
20日内发货
1 mg
¥ 67,300
20日内发货
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产品介绍

生物活性
产品描述
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 41.1 kDa and the accession number is P21730.
生物活性
Measured by its binding ability in a functional ELISA. Immobilized human C5AR1 at 10 μg/mL can bind Anti-C5AR1 recombinant antibody, the EC 50 is 1.239-3.760 ng/mL.
研究背景
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
种属
Human
表达系统
HEK293 Cells
标签C-10xHis (This tag can be tested only under denaturing conditions)
蛋白编号P21730
氨基酸序列MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
蛋白构建1-350 aa
缓冲液PBS, pH 7.4, 6% trehalose
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名CD88, C5R1, C5AR1, C5AR, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR)
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量41.1 kDa (predicted)
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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剂量转换

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技术支持

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关键词

CD 88C5R 1C5AR 1C5a-RC5aR
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