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Anti-CPS1 Antibody (3F443)
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产品编号 TMAC-00952
别名 mitochondrial, Cps1, Carbamoyl-phosphate synthetase I (CPSase I), Carbamoyl-phosphate synthase [ammonia], mitochondrial
Anti-CPS1 Antibody (3F443) 是一种 Rabbit 抗体，靶向 CPS1。Anti-CPS1 Antibody (3F443) 可用于 WB,ICC,IF,IHC,IP。
Anti-CPS1 Antibody (3F443)
Anti-CPS1 Antibody (3F443)
还可以产品编号 TMAC-00952 别名 mitochondrial, Cps1, Carbamoyl-phosphate synthetase I (CPSase I), Carbamoyl-phosphate synthase [ammonia], mitochondrial
Anti-CPS1 Antibody (3F443) 是一种 Rabbit 抗体，靶向 CPS1。Anti-CPS1 Antibody (3F443) 可用于 WB,ICC,IF,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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产品介绍
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抗原信息
化学信息
| 产品描述 | Anti-CPS1 Antibody (3F443) is a Rabbit antibody targeting CPS1. Anti-CPS1 Antibody (3F443) can be used in WB,ICC,IF,IHC,IP. |
| 别名 | mitochondrial, Cps1, Carbamoyl-phosphate synthetase I (CPSase I), Carbamoyl-phosphate synthase [ammonia], mitochondrial |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of CPS1 on SiHa cell using anti-CPS1 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CPS1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-CPS1 antibody. Counter stained with hematoxylin. 4. ICC staining CPS1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The multicomplex protein, carbamoyl-phosphate synthetase-aspartate carbamoyl transferase-dihydro-orotase (CAD), consists of three distinct proteins, carbamoyl phosphate synthetase 2 (CPS2), aspartate transcarbamylase, and dihydro-orotase, which catalyze the second and third steps of pyrimidine biosynthesis. CAD is allosterically regulated by the phosphorylation of CPS2 by cyclic AMP-dependent protein kinase, and this activation enables CPS2 to catalyze the rate-limiting step of pyrimidine synthesis. CAD is expressed in brain and skeletal muscle. A related protein, carbamoyl phosphate synthetase 1 (CPS1) is expressed in liver. CPS1 catalyzes the rate-limiting step in the urea cycle, and deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 165 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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