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Anti-TNF-alpha Antibody-FITC (7S35)

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Anti-TNF-alpha Antibody-FITC (7S35)
产品编号 TMAY-01009F

Anti-TNF-alpha Antibody-FITC (7S35) 是一种 FITC-conjugated Mouse 抗体,靶向 TNF-alpha。Anti-TNF-alpha Antibody-FITC (7S35) 可用于 FCM。

Anti-TNF-alpha Antibody-FITC (7S35)

Anti-TNF-alpha Antibody-FITC (7S35)

Rating icon 还可以
Anti-TNF-alpha Antibody-FITC (7S35)
产品编号 TMAY-01009F

Anti-TNF-alpha Antibody-FITC (7S35) 是一种 FITC-conjugated Mouse 抗体,靶向 TNF-alpha。Anti-TNF-alpha Antibody-FITC (7S35) 可用于 FCM。

规格价格库存数量
25 T
¥ 695
5日内发货
100 T
¥ 1,490
5日内发货
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常见问题解答
溶解度写的“mg/mL”和“mM”是什么意思?
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溶解度中写的“< 1 mg/mL refers to the slightly soluble or insoluble ”是什么意思?
这句话指的是,如果溶解度 < 1 mg/mL,那我们就认为它是微溶或不溶的,这是针对写的“DMSO:Insoluble”或“DMSO:slightly soluble”这类化合物的。
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产品介绍

生物活性
产品描述
Anti-TNF-alpha Antibody-FITC (7S35) is a FITC-conjugated Mouse antibody targeting TNF-alpha. Anti-TNF-alpha Antibody-FITC (7S35) can be used in FCM.
Ig Type
Mouse IgG1
克隆号
7S35
交叉反应
Human
验证活性
Flow cytometric analysis of anti-human TNFα on stimulated PBMC. Human peripheral blood mononuclear cells were stimulated for 6 hrs with Leukocyte Activation Cocktail, with BD GolgiPlug™ (BD Pharmingen™ Cat. No.550583). Cells were then fixed and permeabilized according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), followed by staining with Alexa Fluor® 647 Mouse Anti-Human CD8 (clone RPA-T8, BD Pharmingen™ Cat. No. 557708) and FITC Mouse anti-Human TNFα. The dot plots were derived from gated lymphocytes.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNF-alpha (rh TNF-alpha; TMPY-00936; NP_000585.2; Val 77-Leu 233) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.1% sodium azide
研究背景Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & AntibodyCancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Human TNF-alpha protein (TMPY-00936)
抗原种属
Human
研究领域
Cancer Drug Targets, Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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