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顶部生物活性储存和溶解信息计算器

Anti-DGAT2 Polyclonal Antibody

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产品编号 TMAB-00543
别名 HMFN1045, GS1999full, DKFZp686A15125, Diglyceride acyltransferase 2, Diacylglycerol O-acyltransferase-like protein 2 isoform 1, Diacylglycerol O-acyltransferase homolog 2(mouse), Diacylglycerol O-acyltransferase homolog 2, Diacylglycerol O-acyltransferase 2, Diacylglycerol O acyltransferase like protein 2, DGAT2

Anti-DGAT2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DGAT2。Anti-DGAT2 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

Anti-DGAT2 Polyclonal Antibody

Anti-DGAT2 Polyclonal Antibody

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产品编号 TMAB-00543 别名 HMFN1045, GS1999full, DKFZp686A15125, Diglyceride acyltransferase 2, Diacylglycerol O-acyltransferase-like protein 2 isoform 1, Diacylglycerol O-acyltransferase homolog 2(mouse), Diacylglycerol O-acyltransferase homolog 2, Diacylglycerol O-acyltransferase 2, Diacylglycerol O acyltransferase like protein 2, DGAT2

Anti-DGAT2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DGAT2。Anti-DGAT2 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-DGAT2 Polyclonal Antibody is a Rabbit antibody targeting DGAT2. Anti-DGAT2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
别名HMFN1045, GS1999full, DKFZp686A15125, Diglyceride acyltransferase 2, Diacylglycerol O-acyltransferase-like protein 2 isoform 1, Diacylglycerol O-acyltransferase homolog 2(mouse), Diacylglycerol O-acyltransferase homolog 2, Diacylglycerol O-acyltransferase 2, Diacylglycerol O acyltransferase like protein 2, DGAT2
Ig Type
IgG
交叉反应
Human,Rat (predicted:Mouse,Dog,Cow,Horse,Sheep)
验证活性
1. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with DGAT2 Polyclonal Antibody, Unconjugated (TMAB-00543) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
2. Sample:
Lane 1: Rat Liver tissue lysates
Primary: Anti-DGAT2 (TMAB-00543) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 44 kDa
Observed band size: 44 kDa
verifiedActivityverifiedActivity
应用IFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane.
组织特异性Predominantly expressed in liver and white adipose tissue. Expressed at lower level in mammary gland, testis and peripheral blood leukocytes. Expressed in sebaceous glands of normal skin but decreased psoriatic skin.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DGAT2
抗原种属
Human
基因名称
DGAT2
基因ID
84649
蛋白名称
Diacylglycerol O-acyltransferase 2
Uniprot ID
Q96PD7
研究领域
Metabolism,Fatty acids,Fatty acid oxidation,Lipid metabolism,ER
功能
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation.
化学信息
分子量Theoretical: 44 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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