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Anti-DGAT2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DGAT2。Anti-DGAT2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-DGAT2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DGAT2。Anti-DGAT2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,160 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,780 | 5日内发货 |
产品描述 | Anti-DGAT2 Polyclonal Antibody is a Rabbit antibody targeting DGAT2. Anti-DGAT2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
别名 | HMFN1045, GS1999full, DKFZp686A15125, Diglyceride acyltransferase 2, Diacylglycerol O-acyltransferase-like protein 2 isoform 1, Diacylglycerol O-acyltransferase homolog 2(mouse), Diacylglycerol O-acyltransferase homolog 2, Diacylglycerol O-acyltransferase 2, Diacylglycerol O acyltransferase like protein 2, DGAT2 |
Ig Type | IgG |
交叉反应 | Human,Rat (predicted:Mouse,Dog,Cow,Horse,Sheep) |
验证活性 | 1. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with DGAT2 Polyclonal Antibody, Unconjugated (TMAB-00543) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 2. Sample: Lane 1: Rat Liver tissue lysates Primary: Anti-DGAT2 (TMAB-00543) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kDa Observed band size: 44 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Endoplasmic reticulum membrane. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism. |
免疫原 | KLH conjugated synthetic peptide: human DGAT2 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Metabolism,Fatty acids,Fatty acid oxidation,Lipid metabolism,ER |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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