LILRA4/CD85g Protein, Cynomolgus, Recombinant (His)

LILRA4/CD85g Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.7 kDa and the accession number is XP_005590346.1.

规格	价格/CNY		数量
100 μg	￥ 2,660	5日内发货
500 μg	￥ 10,600	5日内发货
1 mg	￥ 17,800	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 2,660

5日内发货

500 μg

￥ 10,600

5日内发货

1 mg

￥ 17,800

5日内发货

产品描述	LILRA4/CD85g Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.7 kDa and the accession number is XP_005590346.1.

种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	XP_005590346.1
别名	LILRA4, ILT7, CD85g, ILT7MGC129598, MGC129597, ILT-7
蛋白构建	Glu24-Asn446
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	47.7 kDa (predicted). Due to glycosylation, the protein migrates to 58-68 kDa based on Tris-Bis PAGE result.

内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.