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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Klrb1 Polyclonal Antibody

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货号 TMAB-08130

Anti-Klrb1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Klrb1。Anti-Klrb1 Polyclonal Antibody 可用于 WB。

Anti-Klrb1 Polyclonal Antibody

Anti-Klrb1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08130

Anti-Klrb1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Klrb1。Anti-Klrb1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Klrb1 Polyclonal Antibody is a Rabbit antibody targeting Klrb1. Anti-Klrb1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Expressed in a subset of NK cells predominantly in intestinal epithelium and liver. Detected in peripheral blood T-cells and preferentially in adult T-cells with a memory antigenic phenotype.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: rat Klrb1
抗原种属
Rat
基因名称
KLRB1
基因ID
3820
蛋白名称
Killer cell lectin-like receptor subfamily B member 1
功能
Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.
化学信息
分子量Theoretical: 25 kDa. Actual: 40-48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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