购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部生物活性储存和溶解信息计算器

Anti-Phospho-STAT3 (Tyr705) Antibody (2J657)

Rating icon 还可以
产品编号 TMAB-01508
别名 Stat3 (p-Y705), Stat3 (p-Tyr705), signal transducer and activator of transcription 3 (acute-phase response factor), p-Stat3 (Y705), p-Stat3 (Tyr705), Phospho-Stat3 (Y705), HIES, APRF, ADMIO

Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) 是一种 Mouse 抗体，靶向 Phospho-STAT3 (Tyr705)。Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) 可用于 IF,IHC-Fr,IHC-P。

Anti-Phospho-STAT3 (Tyr705) Antibody (2J657)

Anti-Phospho-STAT3 (Tyr705) Antibody (2J657)

Rating icon 还可以
产品编号 TMAB-01508 别名 Stat3 (p-Y705), Stat3 (p-Tyr705), signal transducer and activator of transcription 3 (acute-phase response factor), p-Stat3 (Y705), p-Stat3 (Tyr705), Phospho-Stat3 (Y705), HIES, APRF, ADMIO

Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) 是一种 Mouse 抗体，靶向 Phospho-STAT3 (Tyr705)。Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) is a Mouse antibody targeting Phospho-STAT3 (Tyr705). Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) can be used in IF,IHC-Fr,IHC-P.
别名Stat3 (p-Y705), Stat3 (p-Tyr705), signal transducer and activator of transcription 3 (acute-phase response factor), p-Stat3 (Y705), p-Stat3 (Tyr705), Phospho-Stat3 (Y705), HIES, APRF, ADMIO
Ig Type
IgG
克隆号
2J657
交叉反应
Human,Rat
验证活性
1. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-STAT3 (Tyr705) Monoclonal Antibody, Unconjugated (TMAB-01508) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-STAT3 (Tyr705) Monoclonal Antibody, Unconjugated (TMAB-01508) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Rat Small Intestine; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-STAT3 (Tyr705) Monoclonal Antibody, Unconjugated (TMAB-01508) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Rat Heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-STAT3 (Tyr705) Monoclonal Antibody, Unconjugated (TMAB-01508) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-STAT3 (Tyr705) Monoclonal Antibody, Unconjugated (TMAB-01508) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-STAT3 (Tyr705) Monoclonal Antibody, Unconjugated (TMAB-01508) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
7. Paraformaldehyde-fixed, paraffin embedded Human Tonsil; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-STAT3 (Tyr705) Monoclonal Antibody, Unconjugated (TMAB-01508) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
8. Paraformaldehyde-fixed, paraffin embedded Human Pancreas; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with phospho-STAT3 (Tyr705) Monoclonal Antibody, Unconjugated (TMAB-01508) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.
组织特异性Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human STAT3 around the phosphorylation site of Tyr705
抗原种属
Human
基因名称
STAT3
基因ID
6774
蛋白名称
Signal transducer and activator of transcription 3
Uniprot ID
P40763
研究领域
STAT family,Transcription factors/regulators,Transcription factors,Surface molecules,STATs,Other factors,SARS Coronavirus,STATs,Intracellular
功能
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.
化学信息
分子量Theoretical: 88 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

Stat3 (pY705)Stat3 (pTyr705)Stat3 (phospho-Y705)Stat3 (phospho-Tyr705)pStat3 (Y705)pStat3 (Tyr705)acute-phase response factor

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) | purchase Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) | Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) cost | order Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) | Anti-Phospho-STAT3 (Tyr705) Antibody (2J657) molecular weight