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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody

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货号 TMAB-10606

Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-DOK1 (Tyr362)。Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody 可用于 WB。

Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody

Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10606

Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-DOK1 (Tyr362)。Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody is a Rabbit antibody targeting Phospho-DOK1 (Tyr362). Anti-Phospho-DOK1 (Tyr362) Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cytoplasm. Isoform 3: Cytoplasm, perinuclear region.
组织特异性Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human DOK1 around the phosphorylation site of Tyr362
抗原种属
Human
基因名称
DOK1
基因ID
1796
蛋白名称
Docking protein 1
Uniprot ID
Q99704
功能
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
化学信息
分子量Theoretical: 62 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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