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Anti-KMT2D/ALL1 Polyclonal Antibody

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货号 TMAB-08138

Anti-KMT2D/ALL1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KMT2D/ALL1。Anti-KMT2D/ALL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-KMT2D/ALL1 Polyclonal Antibody

Anti-KMT2D/ALL1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08138

Anti-KMT2D/ALL1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KMT2D/ALL1。Anti-KMT2D/ALL1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-KMT2D/ALL1 Polyclonal Antibody is a Rabbit antibody targeting KMT2D/ALL1. Anti-KMT2D/ALL1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in most adult tissues, including a variety of hematoipoietic cells, with the exception of the liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human KMT2D/ALL1
抗原种属
Human
基因名称
KMT2D
基因ID
蛋白名称
Histone-lysine N-methyltransferase 2D
Uniprot ID
功能
Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
化学信息
分子量Theoretical: 593 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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