Triflupromazine hydrochloride

Name: Triflupromazine hydrochloride
Brand: TargetMol
SKU: T0302
Price: 152 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.82%

货号 T0302Cas号 1098-60-8

别名 盐酸三氟丙嗪, Neoprin, Fluorofen, Fluopromazine hydrochloride, Flumazin

Triflupromazine hydrochloride (Fluopromazine hydrochloride) 是一种抗精神病药物，是多巴胺 D1/D2 受体拮抗剂。

Triflupromazine hydrochloride

一键复制产品信息

很棒

纯度: 99.82%

货号 T0302 别名 盐酸三氟丙嗪, Neoprin, Fluorofen, Fluopromazine hydrochloride, FlumazinCas号 1098-60-8

Triflupromazine hydrochloride (Fluopromazine hydrochloride) 是一种抗精神病药物，是多巴胺 D1/D2 受体拮抗剂。

规格	价格	库存
50 mg	¥ 152	现货
100 mg	¥ 273	现货
200 mg	¥ 491	现货
500 mg	¥ 818	现货
1 g	¥ 1,190	现货

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纯度: 99.82%

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产品介绍

Triflupromazine hydrochloride AI Summary

Triflupromazine hydrochloride exhibits antiplasmodial activity against various strains of Plasmodium falciparum with IC50 values ranging from 6309.57 nM to 12589.25 nM after 72 hours of testing using the SYBR green assay, indicating moderate to potent inhibition of the parasite's growth. Additionally, the compound demonstrates significant inhibitory activity on OATP1B1 and OATP1B3 transporters in CHO cells, showing inhibition rates of 185.58% and 83.79% respectively at a 10 uM concentration using the sodium fluorescein uptake assay. Triflupromazine hydrochloride also shows antiviral activity, as evidenced by a 44.25% inhibition of SARS-CoV-2 induced cytotoxicity in Caco-2 cells at a 10 uM concentration after 48 hours. However, in Vero E6 cells infected with SARS-CoV-2 (strain BavPat1), it displayed a low inhibition of cell viability with an inhibition index of -0.1177 and a similar low inhibition of -0.07% in VERO-6 cells at the same concentration and exposure conditions. The compound's inhibition of SARS-CoV-2 3CL-Pro protease was determined to be -5.673% at a 20 µM concentration..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.
别名	盐酸三氟丙嗪, Neoprin, Fluorofen, Fluopromazine hydrochloride, Flumazin

化学信息

分子量	388.88
分子式	C₁₈H₂₀ClF₃N₂S
CAS No.	1098-60-8
Smiles	Cl.CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (128.57 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5715 mL	12.8574 mL	25.7149 mL	128.5744 mL
5 mM	0.5143 mL	2.5715 mL	5.1430 mL	25.7149 mL
10 mM	0.2571 mL	1.2857 mL	2.5715 mL	12.8574 mL
20 mM	0.1286 mL	0.6429 mL	1.2857 mL	6.4287 mL
50 mM	0.0514 mL	0.2571 mL	0.5143 mL	2.5715 mL
100 mM	0.0257 mL	0.1286 mL	0.2571 mL	1.2857 mL