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Anti-APOB48R Polyclonal Antibody 是一种 Rabbit 抗体,靶向 APOB48R。Anti-APOB48R Polyclonal Antibody 可用于 WB。
Anti-APOB48R Polyclonal Antibody 是一种 Rabbit 抗体,靶向 APOB48R。Anti-APOB48R Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,160 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,780 | 5日内发货 |
产品描述 | Anti-APOB48R Polyclonal Antibody is a Rabbit antibody targeting APOB48R. Anti-APOB48R Polyclonal Antibody can be used in WB. |
疾病造模方案 | |
别名 | Apolipoprotein B48 receptor, Apolipoprotein B-100 receptor, Apolipoprotein B100 receptor, apoB-48R, apoB-100R, apoB100R, APOB, apo b-100 |
Ig Type | IgG |
交叉反应 | Mouse (predicted:Human,Rat,Dog,Rabbit) |
验证活性 | 1. Sample: Blood (Mouse) Cell Lysate at 30 μg Primary: Anti-APOB48R (TMAB-00130) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 115 kDa Observed band size: 115 kDa 2. Sample: Spleen (Mouse) Lysate at 40 μg Primary: Anti-APOB48R (TMAB-00130) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 115 kDa Observed band size: 115 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cell membrane; Peripheral membrane protein. Note=Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein. |
组织特异性 | Expressed in peripheral blood leukocytes > bone marrow = spleen > lymph node, and only faintly visible in appendix and thymus. Expressed in the brain, heart, kidney, liver, lung, pancreas, and placenta. Expressed primarily by reticuloendothelial cells: mo |
构建方式 | Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
浓度 | 1 mg/mL |
研究背景 | APOB48R is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG) rich lipoproteins. It may provide essential lipids, lipid soluble vitamins and other nutrients to reticuloendothelial cells. |
免疫原 | KLH conjugated synthetic peptide: human APOB48R |
抗原种属 | Human |
基因名称 | APOBR |
基因ID | |
蛋白名称 | Apolipoprotein B receptor |
Uniprot ID | |
功能 | Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. |
分子量 | Theoretical: 115 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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