还可以
Anti-CXCL4 Antibody (6I377) 是一种 Mouse 抗体，靶向 CXCL4。Anti-CXCL4 Antibody (6I377) 可用于 ELISA。
还可以Anti-CXCL4 Antibody (6I377) 是一种 Mouse 抗体，靶向 CXCL4。Anti-CXCL4 Antibody (6I377) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,689 | 5日内发货 |
| 产品描述 | Anti-CXCL4 Antibody (6I377) is a Mouse antibody targeting CXCL4. Anti-CXCL4 Antibody (6I377) can be used in ELISA. |
| 别名 | SCYB4, platelet factor 4, PF-4, CXCL4 |
| Ig Type | Mouse IgG1 |
| 克隆号 | 6I377 |
| 交叉反应 | Human |
| 应用 | |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CXCL4/PF4 (rh CXCL4/PF4; TMPY-00741; NP_002610.1; Glu32-Ser101). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, CXCL4/PF4 probably has a role in inflammation and wound repair. This protein is released during platelet aggregation. CXCL4/PF4 neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. CXCL4 is chemotactic for neutrophils and monocytes. It inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. CXCL4/PF4 is up-regulated in human liver fibrosis and that it plays a nonredundant, functional role in experimental liver fibrosis by mediating stellate cell proliferation, migration, and intrahepatic immune cell recruitment. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CXCL4/PF4 Protein (TMPY-00741) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
嗨！有任何问题？点我咨询
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论内容