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Anti-DLC1+DLC2 Polyclonal Antibody

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货号 TMAB-05180

Anti-DLC1+DLC2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DLC1+DLC2。Anti-DLC1+DLC2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-DLC1+DLC2 Polyclonal Antibody

Anti-DLC1+DLC2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05180

Anti-DLC1+DLC2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DLC1+DLC2。Anti-DLC1+DLC2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-DLC1+DLC2 Polyclonal Antibody is a Rabbit antibody targeting DLC1+DLC2. Anti-DLC1+DLC2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Note=Colocalizes with EF1A1 at actin-rich regions in the cell periphery.
组织特异性Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Rho GTPase-activating protein 7
抗原种属
Human
基因名称
DLC1
基因ID
10395
蛋白名称
Rho GTPase-activating protein 7
Uniprot ID
Q96QB1
功能
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
化学信息
分子量Theoretical: 171/122 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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