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Anti-DDX6 Antibody (4T946) 是一种 Rabbit 抗体,靶向 DDX6。Anti-DDX6 Antibody (4T946) 可用于 WB,IHC。
Anti-DDX6 Antibody (4T946) 是一种 Rabbit 抗体,靶向 DDX6。Anti-DDX6 Antibody (4T946) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-DDX6 Antibody (4T946) is a Rabbit antibody targeting DDX6. Anti-DDX6 Antibody (4T946) can be used in WB,IHC. |
别名 | RCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54 |
Ig Type | IgG |
克隆号 | 4T946 |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of DDX6 on different lysates using anti-DDX6 antibody at 1/500 dilution.Positive control:Lane 1: Human colon, Lane 2: SH-SY-5Y, Lane 3: SiHa, Lane 4: K562. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-DDX6 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-DDX6 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-DDX6 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-DDX6 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 54 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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