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Anti-FSTL1 Antibody (4I682) 是一种 Mouse 抗体,靶向 FSTL1。Anti-FSTL1 Antibody (4I682) 可用于 ELISA。
Anti-FSTL1 Antibody (4I682) 是一种 Mouse 抗体,靶向 FSTL1。Anti-FSTL1 Antibody (4I682) 可用于 ELISA。
产品描述 | Anti-FSTL1 Antibody (4I682) is a Mouse antibody targeting FSTL1. Anti-FSTL1 Antibody (4I682) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 4I682 |
交叉反应 | Rat |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat FSTL1 (rR FSTL1; TMPY-04515; NP_077345.1; Met1-Ile306). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling. |
偶联 | Unconjugated |
免疫原 | Recombinant Rat FSTL1 Protein (TMPY-04515) |
抗原种属 | Rat |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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