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As-358 对埃博拉病毒 (IC50 = 47.5 μM) 和马尔堡病毒 (IC50 = 3.7 μM) 具有抑制作用。

As-358 对埃博拉病毒 (IC50 = 47.5 μM) 和马尔堡病毒 (IC50 = 3.7 μM) 具有抑制作用。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 14,900 | 6-8周 | |
| 50 mg | ¥ 19,420 | 6-8周 | |
| 100 mg | ¥ 24,625 | 6-8周 |
| 产品描述 | As-358 has inhibitory effects against Ebola virus (IC50 = 47.5 μM) and Marburg virus (IC50 = 3.7 μM) [1]. |
| 体外活性 | As-358 (compound 3b) (0-500 μM; 10 days) exhibits inhibitory activities against EBOV and MARV [1]. As-358 (0-100 μM; 48 hours) can inhibit WT-EboV-GP and mutant D522A-EboV-GP, with IC 50 s of 1.7 and 2.2 μM, respectively [1]. Cell Proliferation Assay Cell Line: Vero (infected with EBOV and MARV) [1] Concentration: 0-500 μM Incubation Time: 10 days Result: Exhibited inhibitory activities against EBOV and MARV, with IC 50 s of 47.5 ± 8.2 μM and 3.7 ± 1.7 μM, SI values of 9 and 118, respectively. |
| 分子量 | 293.44 |
| 分子式 | C18H31NO2 |
| CAS No. | 2222042-47-7 |
| Smiles | C[C@@]12[C@H](OC(CCN3CCCCC3)=O)C[C@@](C1(C)C)(CC2)[H] |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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