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Anti-SLC7A5 Polyclonal Antibody

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Anti-SLC7A5 Polyclonal Antibody
产品编号 TMAB-01730

Anti-SLC7A5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SLC7A5。Anti-SLC7A5 Polyclonal Antibody 可用于 WB。

Anti-SLC7A5 Polyclonal Antibody

Anti-SLC7A5 Polyclonal Antibody

Rating icon 还可以
Anti-SLC7A5 Polyclonal Antibody
产品编号 TMAB-01730

Anti-SLC7A5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SLC7A5。Anti-SLC7A5 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-SLC7A5 Polyclonal Antibody is a Rabbit antibody targeting SLC7A5. Anti-SLC7A5 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Human (predicted:Mouse,Rat)
验证活性
Sample: Brain (Rat) Lysate at 40 μg
Primary: Anti-SLC7A5 (TMAB-01730) at 1/300 dilution
Secondary: HRP conjugated Goat-Anti-rabbit IgG (secondary antibody) at 1/5000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytosol. Apical cell membrane. Located to the plasma membrane by SLC3A2/4F2hc. Localized to the apical membrane of placental syncytiophoblastic cells. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景L-type amino acid transporter 1 (LAT1) is a multipass-membrane protein responsible for sodium-independent, high-affinity transport of large neutral amino acids. LAT1 functions as a disulfide-linked heterodimer with the amino acid transport protein CD98. LAT1 is expressed predominantly in adult lung and liver but is also expressed in brain, thymus, retina, testis, placenta, bone marrow and fetal liver. In the retina, LAT1 localizes to the blood-retinal-barrier (BRB) and mediates L-leucine transport from the blood to the retina. The devastating effects on the brain caused by phenylketonuria are due to the increased levels of LAT1 on the blood-brain-barrier in response to high concentrations of phenylalanine in the blood. LAT1 accepts the amino-acid related anticancer agent melphalan and plays a significant role in cell proliferation, differentiation, and invasion in esophageal squamous cell carcinoma.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SLC7A5
抗原种属
Human
基因ID
Uniprot ID
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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