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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LAMP1 Antibody (3R897)

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货号 TMAB-01045

别名 lysosomal-associated membrane protein 1

Anti-LAMP1 Antibody (3R897) 是一种 Mouse 抗体，靶向 LAMP1。Anti-LAMP1 Antibody (3R897) 可用于 ELISA, FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB。

Anti-LAMP1 Antibody (3R897)

Anti-LAMP1 Antibody (3R897)

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Rating icon 还可以
货号 TMAB-01045 别名 lysosomal-associated membrane protein 1

Anti-LAMP1 Antibody (3R897) 是一种 Mouse 抗体，靶向 LAMP1。Anti-LAMP1 Antibody (3R897) 可用于 ELISA, FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,565
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-LAMP1 Antibody (3R897) is a Mouse antibody targeting LAMP1. Anti-LAMP1 Antibody (3R897) can be used in ELISA, FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
别名lysosomal-associated membrane protein 1
Ig Type
IgG1, κ
克隆号
3R897
反应种属
Human
验证活性
Sample:
Lane 1: Human HT1080 cell lysates
Lane 2: Human Hela cell lysates
Lane 3: Human U937 cell lysates
Primary: Anti-LAMP1 (TMAB-01045) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 42 kDa
Observed band size: 90-120 kDa
verifiedActivity
应用ELISAFCMICC/IFIFIHC-FrIHC-PWB
推荐剂量
ELISA=1:5000-10000; FCM=1 μg/Test; ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-1000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LAMP1
抗原种属
Human
基因名称
LAMP1
基因ID
3916
蛋白名称
Lysosome-associated membrane glycoprotein 1
Uniprot ID
P11279
研究领域
Signal Transduction,Autophagy,Autophagy and mitophagy,SARS Coronavirus,Growth Cone,Soma marker,Neurogenesis,lamp1,Organelle Proteins,B Lymphocytic Lineage,T Lymphocytic Lineage,Monocytic Lineage,Lysosome
功能
Presents carbohydrate ligands to selectins. Also mplicated in tumor cell metastasis.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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