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Anti-NRAS Antibody (7Y685)
还可以产品编号 TMAY-02221
Anti-NRAS Antibody (7Y685) 是一种 Mouse 抗体，靶向 NRAS。Anti-NRAS Antibody (7Y685) 可用于 WB,ELISA。
Anti-NRAS Antibody (7Y685)
Anti-NRAS Antibody (7Y685)
还可以产品编号 TMAY-02221
Anti-NRAS Antibody (7Y685) 是一种 Mouse 抗体，靶向 NRAS。Anti-NRAS Antibody (7Y685) 可用于 WB,ELISA。
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| 产品描述 | Anti-NRAS Antibody (7Y685) is a Mouse antibody targeting NRAS. Anti-NRAS Antibody (7Y685) can be used in WB,ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7Y685 |
| 交叉反应 | Human |
| 验证活性 | Anti-NRAS mouse monoclonal antibody at 1:500 dilution. -Lane A: A431 Whole Cell Lysate. -Lane B: Mouse brain Tissue lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:21 kDa. -Observed band size:21 kDa |
| 应用 | WB,ELISA |
| 推荐剂量 | WB: 1:500-1:2000; ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NRAS / N-Ras (rh NRAS / N-Ras; TMPY-03487; P01111; Met1-Cys186). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it is activated in HL6, a promyelocytic leukemia line. The mammalian ras gene family consists of the Harvey and Kirsten ras genes (HRAS and KRAS), an inactive pseudogene of each (c-Hras2 and c-Kras1), and the N-ras gene. They differ significantly only in the C-terminal 4 amino acids. These ras genes have GTP/GDP binding and GTPase activity, and their normal function may be as G-like regulatory proteins involved in the normal control of cell growth. The NRAS gene specifies two main transcripts of 2Kb and 4.3Kb. The difference between the two transcripts is a simple extension through the termination site of the 2Kb transcript. The NRAS gene consists of seven exons (-I, I, II, III, IV, V, VI).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human NRAS / N-Ras Protein (TMPY-03487) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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