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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Thioredoxin 2 Polyclonal Antibody

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货号 TMAB-13507

Anti-Thioredoxin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Thioredoxin 2。Anti-Thioredoxin 2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Thioredoxin 2 Polyclonal Antibody

Anti-Thioredoxin 2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13507

Anti-Thioredoxin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Thioredoxin 2。Anti-Thioredoxin 2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Thioredoxin 2 Polyclonal Antibody is a Rabbit antibody targeting Thioredoxin 2. Anti-Thioredoxin 2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion.
组织特异性Widely expressed in adult (at protein level) and fetal tissues.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Thioredoxin 2
抗原种属
Human
基因名称
TXN2
基因ID
25828
蛋白名称
Thioredoxin, mitochondrial
Uniprot ID
Q99757
功能
Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.
化学信息
分子量Theoretical: 12 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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