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Anti-CD204/MSR1 Antibody (7L918) 是一种 Mouse 抗体,靶向 CD204/MSR1。Anti-CD204/MSR1 Antibody (7L918) 可用于 ELISA。
Anti-CD204/MSR1 Antibody (7L918) 是一种 Mouse 抗体,靶向 CD204/MSR1。Anti-CD204/MSR1 Antibody (7L918) 可用于 ELISA。
产品描述 | Anti-CD204/MSR1 Antibody (7L918) is a Mouse antibody targeting CD204/MSR1. Anti-CD204/MSR1 Antibody (7L918) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG2b |
克隆号 | 7L918 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MSR1 (rh MSR1; TMPY-00927; NP_619729.1; Lys 77-Leu 451). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low-density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. |
偶联 | Unconjugated |
免疫原 | Recombinant Human MSR1 protein (TMPY-00927) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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