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IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
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货号 TMPK-00162
别名 Interleukin-1 β, Interleukin-1 beta, IL-1β, IL1F2, IL-1BETA, IL-1B, IL1B, IL-1 β/IL-1F2, IL-1 β, IL-1 beta
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 20.1 kDa and the accession number is P01584.
其他形式的 “IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated”:
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPK-00162 别名 Interleukin-1 β, Interleukin-1 beta, IL-1β, IL1F2, IL-1BETA, IL-1B, IL1B, IL-1 β/IL-1F2, IL-1 β, IL-1 beta
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 20.1 kDa and the accession number is P01584.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 718 | 6-8日内发货 | |
| 10 μg | ¥ 1,180 | 6-8日内发货 | |
| 20 μg | ¥ 1,980 | 5日内发货 | |
| 50 μg | ¥ 3,930 | 5日内发货 | |
| 100 μg | ¥ 6,670 | 5日内发货 | |
| 200 μg | ¥ 11,900 | 5日内发货 | |
| 500 μg | ¥ 26,700 | 5日内发货 |
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| 产品描述 | Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 20.1 kDa and the accession number is P01584. |
| 生物活性 | Immobilized Human IL-1R2, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-1 Beta, His Tag with the EC50 of 13.1ng/ml determined by ELISA. |
| 研究背景 | Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | C-His-Avi |
| 蛋白编号 | P01584 |
| 蛋白构建 | Ala117-Ser269 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | Interleukin-1 β, Interleukin-1 beta, IL-1β, IL1F2, IL-1BETA, IL-1B, IL1B, IL-1 β/IL-1F2, IL-1 β, IL-1 beta |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 20.1 kDa (predicted) same as Tris-Bis PAGE result. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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