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Anti-Siglec-10 Polyclonal Antibody
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产品编号 TMAB-01687
别名 SLG2, SIGLEC10, PRO940, MGC126774
Anti-Siglec-10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Siglec-10。Anti-Siglec-10 Polyclonal Antibody 可用于 WB,ELISA。
Anti-Siglec-10 Polyclonal Antibody
Anti-Siglec-10 Polyclonal Antibody
还可以产品编号 TMAB-01687 别名 SLG2, SIGLEC10, PRO940, MGC126774
Anti-Siglec-10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Siglec-10。Anti-Siglec-10 Polyclonal Antibody 可用于 WB,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 |
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产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-Siglec-10 Polyclonal Antibody is a Rabbit antibody targeting Siglec-10. Anti-Siglec-10 Polyclonal Antibody can be used in WB,ELISA. |
| 疾病造模方案 | |
| 别名 | SLG2, SIGLEC10, PRO940, MGC126774 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | Sample: Lane 1: Mouse Spleen tissue lysates Lane 2: Mouse Lung tissue lysates Lane 3: Human HL-60 cell lysates Lane 4: Human K562 cell lysates Lane 5: Human Jurkat cell lysates Primary: Anti-SIGLEC10 (TMAB-01687) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 77 kDa Observed band size: 100 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform 1, 2, 3, 4: Cell membrane; Single-pass type I membrane protein. Isoform 5: Secreted. |
| 组织特异性 | Expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation). Isoform 5 is found to be the most abundant isoform. Found in lymph node, lung, ovary and appendix. Isoform 1 is found at high levels and isoform 2 a |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).[supplied by OMIM, Jul 2002] |
| 免疫原 | KLH conjugated synthetic peptide: human SIGLEC10 |
| 抗原种属 | Human |
| 基因名称 | SIGLEC10 |
| 基因ID | |
| 蛋白名称 | Sialic acid-binding Ig-like lectin 10 |
| Uniprot ID | |
| 研究领域 | Other Cell Types |
| 功能 | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
| 分子量 | Theoretical: 77 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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