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Anti-PDHE1 Antibody (8V568)

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货号 TMAB-10128

Anti-PDHE1 Antibody (8V568) 是一种 Mouse 抗体，靶向 PDHE1。Anti-PDHE1 Antibody (8V568) 可用于 WB,ICC/IF。

Anti-PDHE1 Antibody (8V568)

Anti-PDHE1 Antibody (8V568)

一键复制产品信息
Rating icon 还可以
货号 TMAB-10128

Anti-PDHE1 Antibody (8V568) 是一种 Mouse 抗体，靶向 PDHE1。Anti-PDHE1 Antibody (8V568) 可用于 WB,ICC/IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-PDHE1 Antibody (8V568) is a Mouse antibody targeting PDHE1. Anti-PDHE1 Antibody (8V568) can be used in WB,ICC/IF.
Ig Type
IgG2a, Kappa
克隆号
8V568
反应种属
Human
应用WBICC/IF
推荐剂量
WB: 1:500-1000; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Mitochondrion matrix.
组织特异性Testis. Expressed in postmeiotic spermatogenic cells.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase(E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
抗原信息
基因名称
PDHA1
蛋白名称
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
功能
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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