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Anti-FKBP1A Polyclonal Antibody

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货号 TMAB-06043

Anti-FKBP1A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FKBP1A。Anti-FKBP1A Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-FKBP1A Polyclonal Antibody

Anti-FKBP1A Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06043

Anti-FKBP1A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FKBP1A。Anti-FKBP1A Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-FKBP1A Polyclonal Antibody is a Rabbit antibody targeting FKBP1A. Anti-FKBP1A Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human FKBP-1A
抗原种属
Human
基因名称
FKBP1A
基因ID
蛋白名称
Peptidyl-prolyl cis-trans isomerase FKBP1A
Uniprot ID
功能
May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
化学信息
分子量Theoretical: 12 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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