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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CD274 Monoclonal Antibody (9E527)

Synonyms: PD-L1, PDL1, PDCD1LG1, PDCD1L1, B7H1, B7-H
货号 TMAT-0352 一键复制产品信息
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Anti-CD274 Monoclonal Antibody (9E527) 是一种 Mouse 抗体，靶向 CD274。Anti-CD274 Monoclonal Antibody (9E527) 可用于 IHC,FCM。

Anti-CD274 Monoclonal Antibody (9E527)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0352

别名 PD-L1, PDL1, PDCD1LG1, PDCD1L1, B7H1, B7-H

Anti-CD274 Monoclonal Antibody (9E527) 是一种 Mouse 抗体，靶向 CD274。Anti-CD274 Monoclonal Antibody (9E527) 可用于 IHC,FCM。

Anti-CD274 Monoclonal Antibody (9E527)
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产品介绍

生物活性
产品描述
Anti-CD274 Monoclonal Antibody (9E527) is a Mouse antibody targeting CD274. Anti-CD274 Monoclonal Antibody (9E527) can be used in IHC,FCM.
别名
PD-L1, PDL1, PDCD1LG1, PDCD1L1, B7H1, B7-H
Ig Type
IgG2b
克隆号
9E527
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD274 (AA: 24-153) expressed in E. Coli.
抗原种属
Human
基因名称
CD274
基因ID
29126
蛋白名称
Programmed cell death 1 ligand 1
Uniprot ID
Q9NZQ7
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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