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Anti-CD8 beta Antibody (6K410) 是一种 Rabbit 抗体,靶向 CD8 beta。Anti-CD8 beta Antibody (6K410) 可用于 IHC-P。
Anti-CD8 beta Antibody (6K410) 是一种 Rabbit 抗体,靶向 CD8 beta。Anti-CD8 beta Antibody (6K410) 可用于 IHC-P。
产品描述 | Anti-CD8 beta Antibody (6K410) is a Rabbit antibody targeting CD8 beta. Anti-CD8 beta Antibody (6K410) can be used in IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6K410 |
交叉反应 | Human |
验证活性 | 1. Immunochemical staining of human CD8B in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CD8B in human lymph node with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:100-1:500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD8B / P37 / LEU2 (rh CD8B / P37 / LEU2; TMPY-02925; P10966-1; Met1-Pro170). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CD8B (CD8b molecule), also known as P37 and LEU2, contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. P37 gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. CD8 is thought to play a role in the process of T-cell mediated killing. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD8B / P37 / LEU2 Protein (TMPY-02925) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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