购物车
- 全部删除
您的购物车当前为空
Anti-DC-SIGN Antibody-HRP (8J205)
还可以产品编号 TMAY-00447H
Anti-DC-SIGN Antibody-HRP (8J205) 是一种 HRP-conjugated Rabbit 抗体，靶向 DC-SIGN。Anti-DC-SIGN Antibody-HRP (8J205) 可用于 ELISA。
Anti-DC-SIGN Antibody-HRP (8J205)
Anti-DC-SIGN Antibody-HRP (8J205)
还可以产品编号 TMAY-00447H
Anti-DC-SIGN Antibody-HRP (8J205) 是一种 HRP-conjugated Rabbit 抗体，靶向 DC-SIGN。Anti-DC-SIGN Antibody-HRP (8J205) 可用于 ELISA。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-DC-SIGN Antibody-HRP (8J205) is a HRP-conjugated Rabbit antibody targeting DC-SIGN. Anti-DC-SIGN Antibody-HRP (8J205) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8J205 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 0.1-1 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD209 / DC-SIGN, (rh CD209 / DC-SIGN; TMPY-00772; NP_066978.1; Lys62-Ala404), and conjugated with horseradish-peroxidase (HRP). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable of binding ICAM-3 on resting T cells in the secondary lymphoid organs, providing the initial contact between these cells during the establishment of cell-mediated immunity. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. It has an important role in mediating DC adhesion, migration, inflammation, activating primary T cell, triggering immune response and participating in immune escape of pathogens and tumors. DC-SIGN also mediates the capture and internalization of viral, bacterial, and fungal pathogens by dendritic cells, such as HIV-1, Ebola virus, cytomegalovirus, Dengue virus, and hepatitis C virus. DC-SIGN is unique in that it regulates adhesion processes, such as DC trafficking and T-cell synapse formation, as well as antigen capture. Moreover, even though several C-type lectins have been shown to bind HIV-1, DC-SIGN does not only capture HIV-1 but also protects it in early endosomes allowing HIV-1 transport by DC to lymphoid tissues, where it enhances trans infection of T cells.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | HRP |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human CD209 / DC-SIGN Protein (TMPY-00772) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-DC-SIGN Antibody-HRP (8J205) | purchase Anti-DC-SIGN Antibody-HRP (8J205) | Anti-DC-SIGN Antibody-HRP (8J205) cost | order Anti-DC-SIGN Antibody-HRP (8J205)
嗨！有任何问题？点我咨询
评论内容