生物活性

产品描述	RNF43 Protein, Canine, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_038533015.1.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
研究背景	RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.
种属	Canine
表达系统	HEK293 Cells
标签	C-His
蛋白编号	XP_0385330151
蛋白构建	Gly24-Tyr197
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4); Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	RNF43, RING-type E3 ubiquitin transferase RNF43, RING finger protein 43, E3 ubiquitin-protein ligase RNF43
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	20.68 kDa (Predicted); 30-40 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

RNF43 Protein, Canine, Recombinant (His)

RNF43 Protein, Canine, Recombinant (His)

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