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Anti-EpCAM/TROP1 Antibody (1I547) 是一种 Rabbit 抗体,靶向 EpCAM/TROP1。Anti-EpCAM/TROP1 Antibody (1I547) 可用于 WB,IHC。
Anti-EpCAM/TROP1 Antibody (1I547) 是一种 Rabbit 抗体,靶向 EpCAM/TROP1。Anti-EpCAM/TROP1 Antibody (1I547) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-EpCAM/TROP1 Antibody (1I547) is a Rabbit antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody (1I547) can be used in WB,IHC. |
别名 | TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5 |
Ig Type | IgG |
克隆号 | 1I547 |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of EpCAM on different lysates using anti-EpCAM antibody at 1/1,000 dilution. Positive control: Lane 1: HCT116, Lane 2: SW480. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-EpCAM antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-EpCAM antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-EpCAM antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-EpCAM antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:100-500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | EPCAM is a carcinoma-associated antigen and belongs to a family which includes at least 2 type I membrane proteins. The EPCAM protein has a role in embryonic stem cells proliferation and differentiation. EPCAM is used as a target for immunotherapy treatment of human carcinomas. EPCAM is expressed on most normal epithelial cells and gastrointestinal carcinomas and acts as a homotypic calcium-independent cell adhesion molecule. Epithelial cell adhesion molecules (EPCAM) can act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for supplying immunological barrier as a first line of defense against mucosal infection. EPCAM gene mutations result in congenital tufting enteropathy. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 35 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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