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Anti-GIT1 Antibody (6X466) 是一种 Rabbit 抗体,靶向 GIT1。Anti-GIT1 Antibody (6X466) 可用于 WB,FCM。
Anti-GIT1 Antibody (6X466) 是一种 Rabbit 抗体,靶向 GIT1。Anti-GIT1 Antibody (6X466) 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-GIT1 Antibody (6X466) is a Rabbit antibody targeting GIT1. Anti-GIT1 Antibody (6X466) can be used in WB,FCM. |
| Ig Type | IgG |
| 克隆号 | 6X466 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Cycles between at least 3 distinct intracellular compartments, including focal adhesions, cytoplasmic complexes and membrane protrusions. During cell migration, when cells detach, moves from the adhesions into the cytoplasmic complexes towards the leading edge, while, when cells adhere, it is found in vinculin-containing adhesions. Recruitment to adhesions may be mediated by active tyrosine-phosphorylated paxillin. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | GTPase-activating protein for ADP ribosylation factor family members, including ARF1. Multidomain scaffold protein that interacts with numerous proteins and therefore participates in many cellular functions, including receptor internalization, focal adhesion remodeling, and signaling by both G protein-coupled receptors and tyrosine kinase receptors.Through PAK1 activation, positively regulates microtubule nucleation during interphase. |
| 免疫原 | A synthesized peptide: human GIT1 |
| 抗原种属 | Human |
| 基因名称 | GIT1 |
| 基因ID | |
| 蛋白名称 | ARF GTPase-activating protein GIT1 |
| Uniprot ID | |
| 功能 | GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. |
| 分子量 | Theoretical: 84 kDa. Actual: 84 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |