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Anti-GIT1 Antibody (6X466)

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货号 TMAB-06489

Anti-GIT1 Antibody (6X466) 是一种 Rabbit 抗体,靶向 GIT1。Anti-GIT1 Antibody (6X466) 可用于 WB,FCM。

Anti-GIT1 Antibody (6X466)

Anti-GIT1 Antibody (6X466)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06489

Anti-GIT1 Antibody (6X466) 是一种 Rabbit 抗体,靶向 GIT1。Anti-GIT1 Antibody (6X466) 可用于 WB,FCM。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-GIT1 Antibody (6X466) is a Rabbit antibody targeting GIT1. Anti-GIT1 Antibody (6X466) can be used in WB,FCM.
Ig Type
IgG
克隆号
6X466
反应种属
Human,Mouse,Rat
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cycles between at least 3 distinct intracellular compartments, including focal adhesions, cytoplasmic complexes and membrane protrusions. During cell migration, when cells detach, moves from the adhesions into the cytoplasmic complexes towards the leading edge, while, when cells adhere, it is found in vinculin-containing adhesions. Recruitment to adhesions may be mediated by active tyrosine-phosphorylated paxillin.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景GTPase-activating protein for ADP ribosylation factor family members, including ARF1. Multidomain scaffold protein that interacts with numerous proteins and therefore participates in many cellular functions, including receptor internalization, focal adhesion remodeling, and signaling by both G protein-coupled receptors and tyrosine kinase receptors.Through PAK1 activation, positively regulates microtubule nucleation during interphase.
抗原信息
免疫原
A synthesized peptide: human GIT1
抗原种属
Human
基因名称
GIT1
基因ID
蛋白名称
ARF GTPase-activating protein GIT1
Uniprot ID
功能
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes.
化学信息
分子量Theoretical: 84 kDa. Actual: 84 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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