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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-C1orf80 Polyclonal Antibody

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货号 TMAB-03361

Anti-C1orf80 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C1orf80。Anti-C1orf80 Polyclonal Antibody 可用于 WB。

Anti-C1orf80 Polyclonal Antibody

Anti-C1orf80 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03361

Anti-C1orf80 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C1orf80。Anti-C1orf80 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-C1orf80 Polyclonal Antibody is a Rabbit antibody targeting C1orf80. Anti-C1orf80 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景AIDA, also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. Expressed in a variety of tissues, including skeletal muscle and heart, AIDA functions as a ventralizing factor during embryogenesis, disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, is important for both JNK signaling and the canonical Wnt pathway, two processes that play an essential role in embryonic dorsoventral patterning. Disruption of Axin by AIDA results in the negative regulation of JNK and Wnt signaling, thereby affecting embryonic developmental events. Three isoforms of AIDA exist due to alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human C1orf180/AIDA
抗原种属
Human
基因名称
AIDA
基因ID
64853
蛋白名称
Axin interactor, dorsalization-associated protein
Uniprot ID
Q96BJ3
功能
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
化学信息
分子量Theoretical: 35 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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