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别名 IP-30, IP30, interferon γ inducible protein 30, interferon gamma inducible protein 30, IFI-30, IFI30, GILT
Anti-IFI30 Antibody (8K242) 是一种 Rabbit 抗体,靶向 IFI30。Anti-IFI30 Antibody (8K242) 可用于 ELISA。
Anti-IFI30 Antibody (8K242) 是一种 Rabbit 抗体,靶向 IFI30。Anti-IFI30 Antibody (8K242) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,279 | 5日内发货 |
| 产品描述 | Anti-IFI30 Antibody (8K242) is a Rabbit antibody targeting IFI30. Anti-IFI30 Antibody (8K242) can be used in ELISA. |
| 别名 | IP-30, IP30, interferon γ inducible protein 30, interferon gamma inducible protein 30, IFI-30, IFI30, GILT |
| Ig Type | Rabbit IgG |
| 克隆号 | 8K242 |
| 交叉反应 | Human |
| 特异性 | Human IFI30 |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IFI30 (rh IFI30; TMPY-02887; P13284; Met1-Lys243). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putative proteins with similarity to GILT. The aligned region contains three conserved cysteine residues. Besides, the two GILT sequences possess a C-X(2)-C motif that is shared by some of the other sequences in the family. This motif is thought to be associated with disulfide bond reduction. IFI30 is a lysosomal thiol reductase that can reduce protein disulfide bonds. It facilitates the generation of MHC class II-restricted epitopes from disulfide bond-containing antigens by the endocytic reduction of disulfide bonds. It also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or cross-presentation. IFI30 may facilitate the complete unfolding of proteins destined for lysosomal degradation and plays an important role in antigen processing. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human IFI30 protein (TMPY-02887) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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