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Anti-USP7 Antibody (8N914)
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产品编号 TMAC-04208
别名 ubiquitin specific peptidase 7 (herpes virus-associated), TEF1, HAUSP
Anti-USP7 Antibody (8N914) 是一种 Rabbit 抗体，靶向 USP7。Anti-USP7 Antibody (8N914) 可用于 WB,IHC,FCM。
Anti-USP7 Antibody (8N914)
Anti-USP7 Antibody (8N914)
还可以产品编号 TMAC-04208 别名 ubiquitin specific peptidase 7 (herpes virus-associated), TEF1, HAUSP
Anti-USP7 Antibody (8N914) 是一种 Rabbit 抗体，靶向 USP7。Anti-USP7 Antibody (8N914) 可用于 WB,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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| 产品描述 | Anti-USP7 Antibody (8N914) is a Rabbit antibody targeting USP7. Anti-USP7 Antibody (8N914) can be used in WB,IHC,FCM. |
| 别名 | ubiquitin specific peptidase 7 (herpes virus-associated), TEF1, HAUSP |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of USP7 on 293T cell using anti-USP7 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-USP7 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-USP7 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-USP7 antibody. Counter stained with hematoxylin. 5. Flow cytometric analysis of PC-3M cells with USP7 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC: 1:50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | HAUSP (herpesvirus-associated ubiquitin-specific protease, USP7) is a ubiquitin-specific protease. HAUSP localizes predominantly to the nucleus, in a TD-dependent manner, where it associates with ND10. ND10 are small nuclear structures implicated in a variety of cellular processes including response to stress and interferons, oncogenesis, and viral infection. HAUSP binds strongly to Vmw110, a herpesvirus regulatory protein which has the ability to disrupt ND10. HAUSP, a novel p53-interacting protein, functions to deubiquitinize p53 in an important pathway for p53 stabilization. HAUSP strongly stabilizes p53 even in the presence of excess Mdm2, and also induces p53-dependent cell growth repression and apoptosis. The HAUSP protein is distributed in the nucleus in a micropunctate pattern with a limited number of larger discrete foci, some of which co-localize with PML in ND10. The gene encoding HAUSP maps to human chromosome band 16p13.2. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: human USP7 aa 100-200 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 128 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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