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Anti-LDLR Antibody-PE (9A669)
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产品编号 TMAY-00501P
别名 low density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH
Anti-LDLR Antibody-PE (9A669) 是一种 PE-conjugated Rabbit 抗体，靶向 LDLR。Anti-LDLR Antibody-PE (9A669) 可用于 FCM。
Anti-LDLR Antibody-PE (9A669)
Anti-LDLR Antibody-PE (9A669)
还可以产品编号 TMAY-00501P 别名 low density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH
Anti-LDLR Antibody-PE (9A669) 是一种 PE-conjugated Rabbit 抗体，靶向 LDLR。Anti-LDLR Antibody-PE (9A669) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 T | ¥ 685 | 5日内发货 | |
| 100 T | ¥ 880 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-LDLR Antibody-PE (9A669) is a PE-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-PE (9A669) can be used in FCM. |
| 别名 | low density lipoprotein receptor, LDLCQ2, LDL Receptor, LDL R, FHC, FH |
| Ig Type | Rabbit IgG |
| 克隆号 | 9A669 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-Human LDLR reactivity on HepG2 cells analyzed by flow cytometry. |
| 应用 | |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human LDL Receptor / LDLR (rh LDL Receptor / LDLR; TMPY-00989; NP_000518.1; Met 1-Arg 788) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL Receptor consists of 840 amino acids (after removal of signal peptide) and mediates the endocytosis of cholesterol-rich LDL. Low-density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. LDL Receptor is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Protein: Human LDL Receptor / LDLR protein (TMPY-00989) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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